CHMP2A polyclonal antibody

• Background:

  CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  BC2; BC-2; VPS2; CHMP2; VPS2A

• Swiss Prot:

  O43633

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human CHMP2A

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB 1:500 - 1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 37 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CHMP2A polyclonal antibody detects endogenous levels of CHMP2A protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using CHMP2A antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4