CHMP2A polyclonal antibody

• Background :

  CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs) . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

• CAS Number :

  9007-83-4

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  BC2; BC-2; VPS2; CHMP2; VPS2A

• Swiss Prot :

  O43633

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human CHMP2A

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB 1:500 - 1:2000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 37 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CHMP2A polyclonal antibody detects endogenous levels of CHMP2A protein.

• Applications Notes :

  Western blot analysis of extracts of various cell lines, using CHMP2A antibody.

• Host or Source :

  Rabbit