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FYB polyclonal antibody

CAT: 0384-BS62547-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62547-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2) . Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ADAP; p120/p130; FYB1; FYB; SLAP130; Adhesion and degranulation promoting adaptor protein; ; Fyb; FYB-120/130; FYN binding protein; FYN-binding protein; FYN-T-binding protein; SLAP-130; SLAP130; SLP-76-associated phosphoprotein
Swiss Prot
O15117
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human FYB.
Conjugation
Unconjugated
Applications
WB
Dilution
WB:1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FYB polyclonal antibody detects endogenous levels of FYB protein.
Applications Notes
Western blot (WB) analysis of FYB polyclonal antibody at 1:500 dilution LaneA:H9C2 whole cell lysate LaneB:SP2/0 whole cell lysate LaneC:PC3 whole cell lysate
Host or Source
Rabbit

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