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BCAP31 polyclonal antibody

CAT: 0384-BS65019-01Size: 50 µLDry Ice: NoHazardous: No
CAT#: BS65019-01Size: 50 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BAP31 (B-cell receptor-association protein 31) is a transmembrane protein associated with the endplasmic reticulum (ER) and ER-Golgi intermediates and has been implicated in protein trafficking and apoptosis. During apoptosis Bap31 is cleaved by caspase-8 at two carboxy-terminal sites which can then direct apoptotic signals between the ER and mitochondria. Association of BAP31 with the anti-apoptotic proteins Bcl-2 or Bcl-xL could function to regulate this ER-mitochondrial pathway. Several studies have shown that BAP31 can control the trafficking of select proteins between the ER and Golgi apparatus and can affect the transport of proteins to the cell surface.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
B-cell receptor-associated protein 31; BCR-associated protein 31; Bap31;6C6-AG tumor-associated antigen; Protein CDM; p28; BCAP31; BAP31; DXS1357E
Swiss Prot
P51572
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to Human BCAP31.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BCAP31 polyclonal antibody detects endogenous levels of BCAP31 protein.
Applications Notes
Western blot (WB) analysis of BCAP31 polyclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate (40ug) Lane2:HepG2 whole cell lysate (40ug) Lane3:The lung tissue lysate of Mouse (40ug)
Host or Source
Rabbit

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