SLC30A8 polyclonal antibody

CAT: 0384-BS65301-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65301-01Size:50 µL
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Background
Solute carrier family 30 member 8 (SLC30A8) Homo sapiens The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
Swiss Prot
Q8IWU4
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range:171-220
Conjugation
Unconjugated
Applications
WB, ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
~ 41 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ZnT-8 Polyclonal Antibody detects endogenous levels of ZnT-8 protein.
Applications Notes
Western Blot analysis of K562 cells using ZnT-8 Polyclonal Antibody. Secondary antibody (catalog#: RS0002) was diluted at 1:20000
Host or Source
Rabbit

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