C1QC polyclonal antibody

• Background:

  Complement C1q C chain (C1QC) Homo sapiens This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Product Name Alternative:

  C1QC; C1QG; Complement C1q subcomponent subunit C

• Swiss Prot:

  P02747

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human C1QC. AA range:81-130

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-p, IF (paraffin section), ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Modification:

  Unmodification

• Molecular Weight:

  ~ 30 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  C1q-C Polyclonal Antibody detects endogenous levels of C1q-C protein.

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using C1QC Antibody. The picture on the right is blocked with the synthesized peptide.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4