C1qa polyclonal antibody

• Background:

  Involved in several processes, including complement-mediated synapse pruning; microglial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is expressed in brain; foot; genitourinary system; and pancreas. Used to study epilepsy and systemic lupus erythematosus. Human ortholog (s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain) .

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  C1q; Adic; C1qa

• Swiss Prot:

  P98086

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 23-245 of mouse C1qa (NP_031598.2) .

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, IF/ICC

• Dilution:

  WB: 1:1000~1:5000 IHC-P: 1:500~1:1000 IF/ICC: 1:100~1:500

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  30KDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  C1qa polyclonal antibody detects endogenous levels of C1qa protein.

• Applications Notes:

  Western blot analysis of various lysates using C1qa pAb at 1:2000 dilution.

• Host or Source:

  Rabbit