Products for Research Use Only

LULL1/TOR1AIP2 Polyclonal Antibody

CAT: 0384-BS65796-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65796-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
TOR1AIP2; IFRG15; Interferon responsive gene 15; LULL1; Lumenal domain like LAP1; NET9; RP11-12M5.5; TOR1AIP2; Torsin 1A interacting protein 2; Torsin A interacting protein 2.
Swiss Prot
Q8NFQ8
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human LULL1:221-320/470
Conjugation
Unconjugated
Applications
WB, IHC-P
Dilution
WB=1:500-2000 IHC-P=1:100-500
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~56kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -31°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LULL1 Polyclonal Antibody detects endogenous levels of LULL1 protein.
Applications Notes
Primary: Anti-LULL1/TOR1AIP2 at 1/300 dilution
Host or Source
Rabbit