ING1 Polyclonal Antibody

• Background:

  This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

• Structure Composition:

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative:

  ING1_HUMAN; Inhibitor of growth protein 1; inhibitor of growth gene 1; Growth inhibitor ING 1; Growth inhibitor ING1; Growth inhibitory protein ING 1; Growth inhibitory protein ING1; Homo sapiens growth inhibitor p33ING1 (ING1) mRNA, complete cds; ING 1; Inhibitor of growth 1; Inhibitor of growth family member 1; Inhibitor of growth protein 1; p24ING1c; p33 ING1; p33ING1; p33ING1b; p47ING1a; Tumor suppressor ING 1; Tumor suppressor ING1.

• Swiss Prot:

  Q9UK53

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH conjugated synthetic peptide derived from human inhibitor of growth gene 1:301-422/422

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB=1:500-2000

• Purity:

  Affinity purified by Protein A

• Modification:

  Unmodification

• Molecular Weight:

  46 kD

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  ING1 Polyclonal Antibody detects endogenous levels of ING1 protein.

• Applications Notes:

  Primary: Anti- ING1 at 1/1000 dilution

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4