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Chordin Polyclonal Antibody

CAT: 0384-BS65703-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65703-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The patterning of the CNS relies on the interaction of multiple signaling molecules such as Sonic Hedgehog, Wnts, and BMPs and their antagonists Chordin and Noggin. At midgastrula, expression of Noggin overlaps that of Chordin. Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The gene which encodeschordin maps to human chromosome 3q27. Noggin is a secreted protein that binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily of signaling proteins, such as BMP-2,4,7. The gene which encodes noggin maps to human chromosome 17q22.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Chordin; Chrd; CHRD_HUMAN; MGC133038; Shortgastrulation protein; SOG
Swiss Prot
Q9H2X0
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human Chordin:412-490/951
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
99kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Chordin Polyclonal Antibody detects endogenous levels of Chordin protein.
Applications Notes
Primary: Anti- Chordin at 1/1000 dilution
Host or Source
Rabbit

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