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MyD88 Polyclonal Antibody

CAT: 0384-BS65652-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65652-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Myeloid differentiation primary response protein MyD88
Swiss Prot
Q99836
Reactivity
Human, Mouse, Rat, Bovine, Monkey, Pig, Sheep
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MYD88.
Conjugation
Unconjugated
Applications
WB IHC IF/ICC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 33, 31, 28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.
Applications Notes
Western blot analysis of MYD88 expression in HEK293T (A), Hela (B), mouse lung (C), mouse muscle (D), mouse spleen (E), rat muscle (F), rat spleen (G) whole cell lysates.
Host or Source
Rabbit

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