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CHPT1 Polyclonal Antibody

CAT: 0384-BS65472-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65472-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHPT1, also known as AAPT1-like protein and Diacylglycerol cholinephosphotransferase 1, is a 406 amino acid multi-pass membrane protein that is localized to the golgi apparatus. By catalyzing the phosphatidylcholine biosynthesis from CDP-choline, it plays an essential role in the formation and maintenance of vesicular membranes. CHPT1 is most abundant in testis, as well as small intestine, heart, colon, spleen and prostate. Expression of CHPT1 is increased in cancerous breast cells as compared to normal breast cell lines and it has been determined that the CHPT1 gene exhibits mutations within the cancerous cells. Interestingly, exposure to mustard gas significantly decreases CHPT1 gene expression and activity, an event that may play an important role in the development of acute respiratory distress syndrome (ARDS) . There are two isoforms of CHPT1 that are produced as a result of alternative splicing events.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
AAPT1-like protein; Cholinephosphotransferase 1; chpt1; CHPT1_HUMAN; Diacylglycerol cholinephosphotransferase 1; hCPT1.
Swiss Prot
Q8WUD6
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human CHPT1:61-160/406
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
50 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CHPT1 Polyclonal Antibody detects endogenous levels of CHPT1 protein.
Applications Notes
Primary: Anti-CHPT1 at 1/1000 dilution
Host or Source
Rabbit

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