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GAP43 (A35) polyclonal antibody

CAT: 0384-BS3655-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3655-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific Elav/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46; GAP43
Swiss Prot
P17677
Reactivity
Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human GAP43.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000~1:5000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GAP43 (A35) polyclonal antibody detects endogenous levels of GAP43 protein.
Applications Notes
Western blot (WB) analysis of GAP43 (A35) polyclonal antibody at 1:2000 dilution Lane1:The Brain tissue lysate of Rat (40ug) Lane2:The Brain tissue lysate of Mouse (40ug)
Host or Source
Rabbit

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