ERp5 polyclonal antibody

• Background:

  May function as a chaperone that inhibits aggregation of misfolded proteins.Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling.May also regulate the UPR via the EIF2AK3 UPR sensor.Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.

• Structure Composition:

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative:

  ERP5; P5; TXNDC7; Protein disulfide-isomerase A6; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7

• Swiss Prot:

  Q15084

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length protein of human ERp5

• Conjugation:

  Unconjugated

• Applications:

  WB, IF/ICC

• Dilution:

  WB (1/500 - 1/2000), IF/ICC (1/50 - 1/100)

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 48 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of ERp5 protein.

• Applications Notes:

  Western blot analysis of ERp5 expression in SW480 (A), HepG2 (B), mouse lung (C), mouse testis (D), rat liver (E) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4