DCLK2 polyclonal antibody

• Background :

  Protein kinase with a significantly reduced C (a2+) /CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity) .

• Structure Composition :

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative :

  DCAMKL2; DCDC3B; DCK2; Serine/threonine-protein kinase DCLK2; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2

• Swiss Prot :

  Q8N568

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human DCLK2. The exact sequence is proprietary.

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC

• Dilution :

  WB (1/500 - 1/2000), IF/IC (1/50 - 1/100)

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 84 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Recognizes endogenous levels of DCLK2 protein.

• Applications Notes :

  Western blot analysis of DCLK2 expression in H1792 (A), mouse testis (B), mouse heart (C) whole cell lysates.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4