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RagA/B polyclonal antibody

CAT: 0384-BS67084-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67084-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade (PubMed:20381137, PubMed:24095279, PubMed:25936802) .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
RRAGA; Ras-related GTP-binding protein A; Rag A; RagA; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1; RRAGB; Ras-related GTP-binding protein B; Rag B; RagB
Swiss Prot
Q7L523; Q5VZM2
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RagA/B. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Translational Contral elF4 and p70 S6 Kinase, MTOR signaling
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IH (1/100 - 1/200)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 35 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of RagA/B protein.
Applications Notes
Western blot analysis of RagA/B expression in mouse lung (A), rat testis (B) whole cell lysates.
Host or Source
Rabbit

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