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CD321 polyclonal antibody

CAT: 0384-NCP0316P-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-NCP0316P-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Junctional Adhesion Molecule-A/F11 Receptor (JAM-A/F11R) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. JAM-A regulates multiple cellular processes, including tight junction assembly, epithelial-mesenchymal transition (EMT), leukocyte migration, virus binding, platelet activation, and angiogenesis. Aberrant expression of JAM-A is correlated with poor patient prognosis in several human cancers. In a mouse model of atherosclerosis, an antagonistic peptide that inhibits JAM-A-expressing platelets from interacting with inflamed endothelial cells reduces atherosclerotic plaque formation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD_antigen: CD321; F11R; JAM1; JCAM; UNQ264/PRO301
Swiss Prot
Q9Y624
Reactivity
Human
Immunogen
Recombinant protein of human CD321.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:2000~1:5000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD321 polyclonal antibody detects endogenous levels of CD321 protein.
Applications Notes
Western blot (WB) analysis of CD321 polyclonal antibody at 1:2000 dilution Lane1:HEK293T whole cell lysate (30ug) Lane2:A549 whole cell lysate (30ug) Lane3:HepG2 whole cell lysate (30ug)
Host or Source
Rabbit

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