Products for Research Use Only
RegisterLogin

RUNX2 polyclonal antibody

CAT: 0384-BS67763-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS67763-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Runt-related transcription factor 2 (RUNX2) is a member of the RUNX family of transcription factors. It is involved in osteoblast differentiation and skeletal morphogenesis. RUNX2 regulates the transcription of various genes, including osteopontin, bone sialoprotein, and osteocalcin, via binding to the core site of the enhancers or promoters. RUNX2 is crucial for the maturation of osteoblasts and both intramembranous and endochondral ossification. Mutations in the corresponding RUNX2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD) . RUNX2 is also abnormally expressed in various human cancers including prostate cancer and breast cancer. It plays an important role in migration, invasion, and bone metastasis of prostate and breast cancer cells.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
AML3; CBFA1; OSF2; PEBP2A; Runt-related transcription factor 2; Acute myeloid leukemia 3 protein; Core-binding factor subunit alpha-1; CBF-alpha-1; Oncogene AML-3; Osteoblast-specific transcription factor 2; OSF-2; Polyomavirus enhancer-binding protein 2 alpha A subunit; PEA2-alpha A; PEBP2-alpha A; SL3-3 enhancer factor 1 alpha A subunit; SL3/AKV core-binding factor alpha A subunit
Swiss Prot
Q13950
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein corresponding to human RUNX2. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/100), IF/ICC (1/50 - 1/100)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 63 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of RUNX2 protein.
Applications Notes
Western blot analysis of RUNX2 expression in Hela (A), mouse testis (B) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS40303RUNX2 Rabbit monoclonal antibody
BS49318-01RUNX2 Recombinant Rabbit mAb
BS49539-01RUNX2 Recombinant Rabbit mAb
BS8826-01RUNX3 polyclonal antibody
BS6873-01RUNX1 polyclonal antibody
BZ16537-01RUNX polyclonal antibody
BS3520-01RUNX3 (R182) polyclonal antibody
BS9227RUNX3 (D196) polyclonal antibody
BS1380-01RUNX1 (H297) polyclonal antibody
BS91186RUNX1/2/3 polyclonal antibody

Alternative Products

CatalogName
MBS2536872-01RUNX2 Polyclonal Antibody
11-8001-100Polyclonal Antibody to RUNX2

Popular Products