RUNX polyclonal antibody

• Background:

  RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  RUNX1; AML1; RUNX2; OSF2; RUNX3; CBFA3

• Swiss Prot:

  Q01196/Q13761/Q13950

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human RUNX1/RUNX2/RUNX3

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, IP, FC

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 49 kDa; Observed MW: 49 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded mouse lung using RUNX1/RUNX2/RUNX3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4