Products for Research Use Only
RegisterLogin

GAD1 polyclonal antibody

CAT: 0384-BS67740-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS67740-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid. GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems and are thought to be involved in synaptic transmission and insulin secretion, respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes. Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2. Mutations in the GAD1 gene can cause autosomal recessive spastic cerebral palsy, possibly attributable to altered glutamate/GABA ratios.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
GAD; GAD67; Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform
Swiss Prot
Q99259
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GAD1. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 66 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of GAD1 protein.
Applications Notes
Western blot analysis of GAD1 expression in Jurkat (A), mouse pancreas (B) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS49348-01GAD1/2 Recombinant Rabbit mAb
BS3870-01Gads (N158) polyclonal antibody
BS6074-01GAD65/GAD2 polyclonal antibody
BS9140GADD 45γ (S123) polyclonal antibody
BS1135-01GAD-67 (A492) polyclonal antibody
BS1400-01GAD-65/67 (D572) polyclonal antibody
MB66620GAD2 monoclonal antibody
MB67075-01GAD2 monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody

Alternative Products

CatalogName
MBS2519172-01GAD1 Polyclonal Antibody
AMM04663GPolyclonal GAD1 Antibody
GTR17878999GAD1 Rabbit Polyclonal Antibody
GTR18045778-01GAD67/GAD1 polyclonal antibody
35-1793-50Polyclonal Antibody to GAD67 (GAD1)
ANT-12279-50ugGAD1 / GAD67 Polyclonal Antibody
E55A02955GAD1/GAD67 Polyclonal Antibody

Popular Products