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Dicer polyclonal antibody

CAT: 0384-BS67544-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67544-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) . After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha , pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs . The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
DICER; HERNA; KIAA0928; Endoribonuclease Dicer; Helicase with RNase motif; Helicase MOI
Swiss Prot
Q9UPY3
Reactivity
Human, Mouse
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Dicer. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 260 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of Dicer protein.
Applications Notes
Western blot analysis of Dicer expression in mouse testis (A), EC9706 (B), HEK293T (C), MCF7 (D) whole cell lysates.
Host or Source
Rabbit

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