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Histone H2A polyclonal antibody

CAT: 0384-BS67537-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67537-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
H2AFP; H2AFC; H2AFD; H2AFI; H2AFN; Histone H2A type 1; H2A.1; Histone H2A/p
Swiss Prot
P0C0S8
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Monkey
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Histone H2A. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 15 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of Histone H2A protein.
Applications Notes
Western blot analysis of Histone H2A expression in U87MG (A), A549 (B), SGC7901 (C), rat lung (D), mouse brain (E) whole cell lysates.
Host or Source
Rabbit

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