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Fetuin A polyclonal antibody

CAT: 0384-BS67509-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67509-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fetuin A is produced by liver and secreted to plasma, and selectively concentrated in bone matrix. It is synthesized as a precursor and processed to generate 2 chains that are held together by a disulfide bond. It is a systemically acting calcification inhibitor . Reduced level of fetuin A in serum is associated with increased cardiovascular mortality in dialysis patients . Fetuin A can inhibit insulin-induced tyrosine phosphorylation of the insulin receptor tyrosine kinase and insulin receptor substrate-1 . Fetuin A deficient mice show high insulin sensitivity and high levels of serum fetuin A are associated with insulin resistance in humans .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
FETUA; Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A
Swiss Prot
P02765
Reactivity
Human, Mouse, Rat, Bovine, Sheep
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Fetuin A. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of Fetuin A protein.
Applications Notes
Western blot analysis of Fetuin A expression in PC12 (A), AML12 (B), HEK293T (C), H1792 (D) whole cell lysates.
Host or Source
Rabbit

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