CDCA7L polyclonal antibody

• Background:

  Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CDCA7L; JPO2; R1; RAM2

• Swiss Prot:

  Q96GN5

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CDCA7L (NP_061189.2) .

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB,1:200 - 1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  52kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Unmodification

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4