Dnmt1 polyclonal antibody

• Background:

  Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2.

• Structure Composition:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Product Name Alternative:

  ADCADN; CXXC finger protein 9; CXXC9; DNA methyltransferase 1; DNA MTase; Dnmt1o; HSN1E; M.HsaI; MCMT; Met1; MommeD2

• Swiss Prot:

  P26358

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human Dnmt1

• Conjugation:

  Unconjugated

• Applications:

  FC, WB

• Dilution:

  WB: 1/500-1/1000 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 183 kDa; Observed MW: 183 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of DNMT1 in Jurkat lysates using Dnmt1 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4