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ADAM10 polyclonal antibody

CAT: 0384-BZ16999-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16999-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways.
CAS Number
9007-83-4
Structure Composition
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Product Name Alternative
CDw156; CD156c; ADAM10; KUZ; MADM
Swiss Prot
O14672
Reactivity
Human
Immunogen
A synthetic peptide of human ADAM10
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB: 1/500-1/1000 IP: 1/20
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 84 kDa; Observed MW: 90,68 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of ADAM10 in NTERA-2 lysates using ADAM10 antibody.
Host or Source
Rabbit

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