CNOT7 polyclonal antibody

• Background:

  Has 3'-5' poly (A) exoribonuclease activity for synthetic poly (A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

• Structure Composition:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Product Name Alternative:

  CCR4-associated factor 1; CAF-1

• Swiss Prot:

  Q60809

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  A synthetic peptide of mouse CNOT7

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, FC, IP

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 33 kDa; Observed MW: 33 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of CNOT7 in F9, C6, PC-12, 3T3, Raw264.7 lysates using CNOT7 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4