DDB1 polyclonal antibody

• Background:

  Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex) . The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1

• Swiss Prot:

  Q16531

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human DDB1

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, IP

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 127 kDa; Observed MW: 127 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of DDB1 in HeLa lysates using DDB1 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4