Islet 1 polyclonal antibody

• Background :

  ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  ISL1; Insulin gene enhancer protein ISL-1; Islet-1

• Swiss Prot :

  P61371

• Reactivity :

  Human

• Immunogen :

  A synthesized peptide derived from human Islet1

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P, ICC/IF, IP, FC

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 39 kDa; Observed MW: 39 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of Islet1 in HeLa lysates using Islet 1 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4