VPS35 polyclonal antibody

• Background:

  Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) .

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  HVPS35; MEM3; PARK17; VPS35

• Swiss Prot:

  Q96QK1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human VPS35

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, FC

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 92 kDa; Observed MW: 92 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of VPS35 in HeLa lysates; mouse kidney lysates using VPS35 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4