USP13 polyclonal antibody

• Background:

  Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13

• Swiss Prot:

  Q92995

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthesized peptide derived from human USP13

• Conjugation:

  Unconjugated

• Applications:

  WB, ICC/IF, IP, FC

• Dilution:

  WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 97 kDa; Observed MW: 97 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of USP13 in HepG2 lysates using USP13 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4