USP13 polyclonal antibody

• Background :

  Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  Deubiquitinating enzyme 13; Isopeptidase T3; ISOT3; UBP13; USP13

• Swiss Prot :

  Q92995

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthesized peptide derived from human USP13

• Conjugation :

  Unconjugated

• Applications :

  WB, ICC/IF, IP, FC

• Dilution :

  WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 97 kDa; Observed MW: 97 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of USP13 in HepG2 lysates using USP13 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4