USP10 polyclonal antibody

• Background:

  Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  Deubiquitinating enzyme 10; UBPO; USP10

• Swiss Prot:

  Q14694

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human USP10

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, IP

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 87 kDa; Observed MW: 110 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of USP10 in A375 lysates using USP10 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4