Human IgA polyclonal antibody

• Background:

  Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region

• Swiss Prot:

  P01876/P01877

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human IgA

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, ICC/IF, IP

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 60 kDa; Observed MW: 60 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of IgA in Human plasma lysates using Human IgA antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4