ASH2L polyclonal antibody

• Background :

  Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  ASH2; Bre2; ASH2L1; ASH2L2

• Swiss Prot :

  Q9UBL3

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human ASH2L

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P, ICC/IF

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 69 kDa; Observed MW: 69 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of ASH2L in K562 lysates using ASH2L antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4