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Polyclonal Antibody to ASH2L

CAT: 0793-35-1719-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1719-50Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Product Name Alternative
ASH2|| Bre2|| ASH2L1|| ASH2L2
Gene Name
ASH2L
Gene ID
9070
UniProt
Q9UBL3
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.620~624 (G-R-R-S-P) derived from Human ASH2L.
Target Antigen
ASH2L
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 65 80kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · Q9UBL3

Set1/Ash2 histone methyltransferase complex subunit ASH2

ASH2L_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBL3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ASH2L
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K7C3, D3DSW9, O60659, O60660, Q96B62
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDNA-binding

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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Alternative Products

CatalogName
MBS8571674-01ASH2L Polyclonal Antibody
NBP2-15488Rabbit Polyclonal ASH2L Antibody

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