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IDO 2 polyclonal antibody

CAT: 0384-BZ16211-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16211-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
IDO2; INDOL1; Indoleamine 2; 3-dioxygenase 2; IDO-2; Indoleamine 2; 3-dioxygenase-like protein 1; Indoleamine-pyrrole 2; 3-dioxygenase-like protein 1
Swiss Prot
Q6ZQW0
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IDO2. AA range:101-150
Conjugation
Unconjugated
Applications
WB, ELISA
Dilution
WB: 1/500-1/1000 ELISA: 1/10000
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 47 kDa; Observed MW: 47 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of IDO 2 in HeLa, HepG2 lysates using IDO 2 antibody.
Host or Source
Rabbit

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