C-Jun (10G2) monoclonal antibody

• Background:

  C-jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39

• Swiss Prot:

  P05412

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic peptide conjugated to KLH.

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Dilution:

  IHC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG1

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using c-Jun antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

• Host or Source:

  Mouse

• CAS Number:

  9007-83-4