CD146 polyclonal antibody

CAT: 0384-NCP0270P-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-NCP0270P-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD146
Swiss Prot
P43121
Reactivity
Human
Immunogen
Recombinant protein of human CD146.
Conjugation
Unconjugated
Applications
WB IP IF
Dilution
WB: 1:2000~1:5000 IF 1:50~1:200 IP 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD146 polyclonal antibody detects endogenous levels of CD146 protein.
Applications Notes
Western blot (WB) analysis of CD146 polyclonal antibody at 1:2000 dilution Lane1:L02 cell membrane lysate (20ug) Lane2:A549 cell membrane lysate (20ug) Lane3:MCF-7 cell membrane lysate (20ug)
Host or Source
Rabbit

Related Products

CatalogName
BS7708-01CD146/MCAM polyclonal antibody
BS77232CD146/MCAM polyclonal antibody
BS78184CD146/MCAM polyclonal antibody
BS76998CD146/MCAM polyclonal antibody
BS77909CD146/MCAM polyclonal antibody
MB10379CD146 monoclonal antibody
NCP0270-01CD146 Recombinant Protein
BS45786CD146 Recombinant Rabbit mAb
BS45527-01CD146 Recombinant Rabbit mAb
NCP0177P-01CD147 polyclonal antibody

Alternative Products

CatalogName
MBS2564418-01CD146 Polyclonal Antibody
MBS2575066-01CD146/MCAM Polyclonal Antibody
APRab00371-01CD146 Rabbit Polyclonal Antibody
ANT-10778-50ugCD146 / MCAM Polyclonal Antibody
GWB-BBP611Polyclonal Anti- CD146 Antibody
MF-0069112-01Anti-CD146 Polyclonal Antibody
NBP1-88132Rabbit Polyclonal MCAM/CD146 Antibody
bs-1618R-PerCP-01CD146 Polyclonal Antibody, PerCP Conjugated
bs-1618R-Cy3-TRCD146 Polyclonal Antibody, Cy3 Conjugated
bs-1618R-Cy5-TRCD146 Polyclonal Antibody, Cy5 Conjugated

Popular Products