Products for Research Use Only

CD79A polyclonal antibody

CAT: 0384-NCP0227P-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-NCP0227P-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
B-cell antigen receptor complex-associated protein alpha chain; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein; CD79a
Swiss Prot
P11912
Reactivity
Rat, Mouse, Human
Immunogen
Recombinant protein of human CD79A.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:2000~1:5000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 45 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD79A polyclonal antibody detects endogenous levels of CD79A protein.
Applications Notes
Western blot (WB) analysis of CD79A polyclonal antibody at 1:2000 dilution Lane1:C6 whole cell lysate (30ug) Lane2:CT-26 whole cell lysate (30ug) Lane3:SGC7901 whole cell lysate (30ug) Lane4:EC9706 cell membrane lysate (30ug) Lane5:MCF-7 cell membrane lysate (30ug)
Host or Source
Rabbit