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CD1D polyclonal antibody

CAT: 0384-NCP0188P-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-NCP0188P-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The CD1 multigene family encodes five forms of the CD1 T cell surface glyco_x0002_protein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 mem_x0002_brane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 anti_x0002_gens are associated with b-2-Microglobulin and expressed on cortical thymo_x0002_cytes, Langerhans cells, a B cell subset and some dendritic cells. Adaptor pro_x0002_tein complexes and CD1-associated chaperones control CD1 trafficking and the development and activation of CD1-restricted T cells. CD1D is present on human intestinal epithelial cells (IEC) and exists as a b-2-Microglobulin_x0002_independent nonglycosylated form or a b-2-Microglobulin-dependent glycosy_x0002_lated form. The human CD1D gene maps to chromosome 1q23.1 and encodes a 335 amino acid protein that influences normal T cell maturation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Antigen-presenting glycoprotein CD1d; R3G1; CD1d; CD1D
Swiss Prot
P15813
Reactivity
Human
Immunogen
Recombinant protein of human CD1D.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:2000~1:5000 IF 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD1D polyclonal antibody detects endogenous levels of CD1D protein.
Applications Notes
Western blot (WB) analysis of CD1D polyclonal antibody at 1:2000 dilution Lane1:L02 cell membrane lysate (24ug) Lane2:A549 cell membrane lysate (24ug)
Host or Source
Rabbit

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