SDHA polyclonal antibody

• Background:

  This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  SDHA; CMD1GG; FP; PGL5; SDH1; SDH2; SDHF

• Swiss Prot:

  P31040

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length protein of human SDHA.

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF/ICC

• Dilution:

  WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 70 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  SDHA polyclonal antibody detects endogenous levels of SDHA protein.

• Applications Notes:

  Western blot analysis of SDHA expression in HepG2 (A), MCF7 (B), mouse liver (C), mouse stomach (D) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4