CDK6 polyclonal antibody

• Background:

  Cdk6 is known to associate with cyclins D1, D2 and D3 and to be involved with the G1/S transition of the cell cycle. Multiple inhibitors of Cdk6 have been identified, including p18 and p19. These inhibitors bind to both free and complexed Cdk6, and they inhibit the activity of the cyclin D-bound Cdk6.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CDK 6; CDK6; CDK6; Cell division protein kinase 6; Crk 2; Crk2; Cyclin dependent kinase 6; Cyclin-dependent kinase 6; MGC59692; p40; PLSTIRE; Serine/threonine protein kinase PLSTIRE; Serine/threonine-protein kinase PLSTIRE; STQTL11

• Swiss Prot:

  Q00534

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length protein of human CDK6.

• Conjugation:

  Unconjugated

• Related Pathways:

  Cell Cycle Control G1 S Checkpoint

• Applications:

  WB IHC IF/ICC

• Dilution:

  WB: 1:500~1:2000 IHC: 1:50~1:200 IF/ICC: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 37 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CDK6 polyclonal antibody detects endogenous levels of CDK6 protein.

• Applications Notes:

  Western blot analysis of CDK6 expression in Jurkat (A), K562 (B) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4