CD141 polyclonal antibody

• Background :

  CD141/Thrombomodulin (TM, THBD, BDCA-3) is an integral membrane protein expressed on the surface of endothelial cells. Acting as a cofactor with Thrombin, CD141/Thrombomodulin activates and initiates the Protein C anticoagulant pathway. CD141/Thrombomodulin is expressed by a small subset of human CD11c+ myeloid dendritic cells. These CD141+XCR1+ dendritic cells cross-present antigens to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative :

  Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

• Swiss Prot :

  P07204

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human CD141.

• Conjugation :

  Unconjugated

• Applications :

  IF

• Dilution :

  IF: 1:100~1:500

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodified

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CD141 polyclonal antibody detects endogenous levels of CD141 protein.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4