CD79B polyclonal antibody

• Background:

  Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative:

  B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD79b

• Swiss Prot:

  P40259

• Reactivity:

  Rat, Mouse

• Immunogen:

  Recombinant protein of human CD79B.

• Conjugation:

  Unconjugated

• Related Pathways:

  B cell receptor signaling

• Applications:

  WB IF

• Dilution:

  WB: 1:10000~1:20000 IF: 1:100~1:500

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 30 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CD79B polyclonal antibody detects endogenous levels of CD79B protein.

• Applications Notes:

  Western blot (WB) analysis of CD79B polyclonal antibody at 1:10000 dilution Lane1:The liver tissue lysate of Rat (30ug) ) Lane2:The heart tissue lysate of Mouse (30ug) )

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4