Products for Research Use Only
RegisterLogin

Desipramine-d3

CAT: 0804-HY-B1272AS1Size: 2.5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1272AS1Size:2.5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Desipramine-d3 is the deuterium labeled Desipramine. Desipramine is a tricyclic psychotic compound, possessing antidepressant activity. Desipramine inhibits the norepinephrine reuptake receptor in the central nervous system and reduces the sleep-related loss of genioglossus activity, can be used to research the improvement of pharyngeal collapsibility[1][2][3].
CAS Number
65100-49-4
UNSPSC
12352005
Hazard Statement
H302-H410
Target
Dopamine Transporter; Serotonin Transporter
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])NCCCN1C2=CC=CC=C2CCC3=CC=CC=C31
Molecular Formula
C18H19D3N2
Molecular Weight
269.40
Precautions
P264-P270-P273-P330-P391-P501
References & Citations
[1]Garcia AS, et al. Autoreceptor-mediated inhibition of norepinephrine release in rat medial prefrontal cortex is maintained after chronic desipramine treatment. J Neurochem. 2004 Nov;91 (3) :683-93. |[2]Taranto-Montemurro L, et al. Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation. Eur Respir J. 2016 Nov;48 (5) :1340-1350. |[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B1272ADesipramine
HY-B1272AS-01Desipramine-d4
HY-B1272-01Desipramine (hydrochloride)
HY-B1272R-01Desipramine (hydrochloride) (Standard)
HY-132461S1-012-Hydroxy Desipramine-d6
HY-15398S3-01Vitamin D3-d3
HY-132348S1Granisetron-d3 (1-methyl-d3)
HY-150954SL-Methionine-d3 (S-methyl-d3) Methyl-d3-sulfonium Chloride
HY-W758392(±) -Ipratropium-d3 Bromide (N-methyl-d3)
HY-B1213AS-01Trimipramine-d3 (N-methyl-d3) (maleate)

Alternative Products

CatalogName
TRC-D290053-25MGDesipramine-d3
TMIH-0184-01Desipramine-d3 HCl
sc-2138202-Hydroxy Desipramine-d3
sc-2138212-Hydroxy Desipramine-d3 β-D-Glucuronide
T60445-01Desipramine
TRC-H936512-50MG2-Hydroxy Desipramine-d3 beta-D-Glucuronide
20-1517Desipramine antibody
80-1315Desipramine-HRP
226913Desipramine (HRP)
B2987-10Desipramine hydrochloride

Popular Products