Cefuroxime

• UNSPSC Description:

  Cefuroxime is an orally active second-generation cephalosporin antibiotic with increased stability to β-lactamase. Cefuroxime has a broad spectrum activity against Gram-positive and Gram-negative bacteria[1].

• Target Antigen:

  Antibiotic; Bacterial; Beta-lactamase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cefuroxime.html

• Purity:

  99.08

• Solubility:

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles:

  O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)O

• Molecular Weight:

  424.39

• References & Citations:

  [1]Callaghan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vitro. Antimicrob Agents Chemother. 1976 Mar;9(3):511-9.|[2]D M Ryan, et al. Cefuroxime, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9(3):520-5.Adv Funct Mater. 2024 Jun 19.|Nat Commun. 2022 Mar 2;13(1):1116.|Nat Commun. 2023 Mar 22;14(1):1594.|Biomed Res Int. 2018 Jul 2;2018:3579832. |Int J Antimicrob Agents. 2024 May 30:107229.|J Chem Inf Model. 2021 Mar 18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  55268-75-2