Fludrocortisone-d5

• Description :

  Fludrocortisone-d5 is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

• Product Name Alternative :

  9α-Fludrocortisone-d5; 9α-Fluorcortisol-d5

• UNSPSC :

  12352211

• Target :

  Isotope-Labeled Compounds; Mineralocorticoid Receptor

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Inflammation/Immunology

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@](C(C([2H])([2H])O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O

• Molecular Formula :

  C21H24D5FO5

• Molecular Weight :

  385.48

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Jaal J, et al. Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone. Case Rep Oncol Med. 2015;2015:286029.|[3]Mori T, et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery [1999, 91 (6) :947-952]

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported