Fludrocortisone-d5

CAT: 0804-HY-B1203S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1203S-01Size:1 mg
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Description
Fludrocortisone-d5 is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.
Product Name Alternative
9α-Fludrocortisone-d5; 9α-Fluorcortisol-d5
UNSPSC
12352211
Target
Isotope-Labeled Compounds; Mineralocorticoid Receptor
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C(C([2H])([2H])O)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O
Molecular Formula
C21H24D5FO5
Molecular Weight
385.48
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Jaal J, et al. Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone. Case Rep Oncol Med. 2015;2015:286029.|[3]Mori T, et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery [1999, 91 (6) :947-952]
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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