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Fludrocortisone

CAT: 0804-HY-B1203-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1203-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fludrocortisone inhibits natriuresis. Fludrocortisone is a synthetic mineralocorticoid with anti-inflammatory activity. Fludrocortisone can be studied in research for small cell lung cancer with profound hyponatremia and acute neurological symptoms as well as aneurysmal subarachnoid hemorrhage[1][2].
CAS Number
127-31-1
Product Name Alternative
9α-Fludrocortisone; 9α-Fluorcortisol
UNSPSC
12352211
Hazard Statement
H302, H312, H332, H361
Target
Mineralocorticoid Receptor; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Fludrocortisone.html
Purity
98.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3(F)[C@@H](O)C2)=O
Molecular Formula
C21H29FO5
Molecular Weight
380.45
Precautions
H302, H312, H332, H361
References & Citations
[1]Jaal J, et al. Small Cell Lung Cancer Patient with Profound Hyponatremia and Acute Neurological Symptoms: An Effective Treatment with Fludrocortisone. Case Rep Oncol Med. 2015;2015:286029.|[2]Mori T, et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery [1999, 91 (6) :947-952]
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
BA7985-5Fludrocortisone
FF23322-01Fludrocortisone acetate

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