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Temephos-d12

CAT: 0804-HY-B1120SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1120SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
CAS Number
[1219795-39-7]
Product Name Alternative
Temefos-d12
UNSPSC
12352005
Target
Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OP(OC(C=C1)=CC=C1SC(C=C2)=CC=C2OP(OC([2H])([2H])[2H])(OC([2H])([2H])[2H])=S)(OC([2H])([2H])[2H])=S
Molecular Formula
C16H8D12O6P2S3
Molecular Weight
478.54
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Thirugnanam M, et al. Environmental impact of mosquito pesticides: influence of temefos on the brain acetylcholinesterase of killifish. Environ Physiol Biochem. 1975;5 (6) :451-9.|[3]Wirth MC, et al. Selection and characterization of temephos resistance in a population of Aedes aegypti from Tortola, British Virgin Islands. J Am Mosq Control Assoc. 1999 Sep15 (3) :315-20.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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