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Clofazimine-d7

CAT: 0804-HY-B1046SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1046SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clofazimine-d7 is deuterium labeled Clofazimine. Clofazimine is an iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial agents to treat AIDS and Crohn's disease.
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.0
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(N2C3=C/C(C(NC4=CC=C(Cl)C=C4)=CC3=NC5=C2C=CC=C5)=N\C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1
Molecular Formula
C27H15D7Cl2N4
Molecular Weight
480.44
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Arbiser JL, et al. Clofazimine: a review of its medical uses and mechanisms of action. J Am Acad Dermatol. 1995 Feb;32 (2 Pt 1) :241-7.|[3]Cholo MC, et al. Clofazimine: current status and future prospects. J Antimicrob Chemother. 2012 Feb;67 (2) :290-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported