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Dioxybenzone-d3

CAT: 0804-HY-B0966SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0966SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dioxybenzone-d3 is deuterium labeled Dioxybenzone. Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study[1][2][3][4].
Product Name Alternative
Benzophenone-8-d3; UV-24-d3
UNSPSC
12352005
Target
Biochemical Assay Reagents; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(OC([2H])([2H])[2H])C=C1O)C2=CC=CC=C2O
Molecular Formula
C14H9D3O4
Molecular Weight
247.26
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Rao GS, et al. Oral chemoprevention of skin cancer in mice by benzophenone sunscreens dioxybenzone and octabenzone in drinking water. Anticancer Res. 2013 Jun;33 (6) :2535-40.|[3]Zhan T, et al. Transcriptome aberration in mice uterus associated with steroid hormone response and inflammation induced by dioxybenzone and its metabolites. Environ Pollut. 2021 Oct 1;286:117294.|[4]Sherwood VF, et al. Altered UV absorbance and cytotoxicity of chlorinated sunscreen agents. Cutan Ocul Toxicol. 2012 Dec;31 (4) :273-9.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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